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In some ways, we know aging when we see it, from the graying of hair to the wrinkling of skin to declines in motor, sensory, and cognitive capacities. Yet the underlying biology of aging remains a matter of uncertainty and debate. Many lines of research align with the theory that aging is a direct result of decay — the inevitable degradation of molecules (including proteins o...


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At the quantum scale, tiny particles behave in bizarre ways. One reason for this is the uncertainty principle, which says that the more you know about where a quantum particle is, the less you can know about how fast it’s moving, and vice versa. Recently, this rule got a rare upgrade. The new uncertainty principle relates to fractals, shapes that remain equally complex no mat...


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A river has my heart. It’s not the austere, black Thames winding through London, where I was born, but a lazy green one 5,000 miles away, where I spent my adolescence: the Blanco River in Texas. My maternal ancestors have dipped into its waters for generations, as I have on countless summer days. The Blanco is a tributary of the San Marcos, which flows into the Guadalupe, and...


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In a laboratory 2 kilometers underground, a crane lowers Matt Depatie, a detector technologist, through a hatch into a white-walled cavern filled with about 7,000 tons of ultrapure water that glows as blue as wiper fluid in the light. “Splashdown,” Depatie says over a radio as he steps into an inflatable raft waiting below. Normally, the cavern is one of the darkest places on...


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Pain and pleasure seem like simple facts of life, but they are far from it. Neuroscientists still cannot say why physical pain differs from psychological pain, for instance, nor why a loved one’s touch soothes while a stranger’s touch repels. To explore the science behind these sensations, Janna Levin talked to Ishmail Abdus-Saboor, a neuroscientist at Columbia University’s Z...


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