HemOnc.org - A Hematology Oncology Wiki - Recent changes [en]

Created page with "== General information and mechanism of action == From the NCI Thesaurus: "A genetically modified oncolytic viral strain of the herpes simplex type 1 (HSV-1) virus, with potential oncolytic, immunostimulating and antineoplastic activities. Upon administration, vusolimogene oderparepvec specifically targets, infects and replicates in tumor cells only while n...

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Created page with "== General information and mechanism of action == Class/mechanism from the NCI Thesaurus: "A modulator of the E3 ubiquitin ligase complex containing cereblon (CRL4-CRBN E3 ubiquitin ligase), with immunomodulating and pro-apoptotic activities. Upon administration, iberdomide specifically binds to the cereblon (CRBN) part of the ligase complex, thereby affect...

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