Chacko's Critical Care Blogspot

On my rounds this morning, one of the first patients I see is an elderly gentleman who underwent multiple debridements on his diabetic foot. He had been on ventilator support, septic, and had edged close to requiring dialysis for his failing kidneys. The surgeons had done a thorough job cutting out the dead bits and…

The LOGICAL Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Conservative Oxygen for Unresponsive Patients after Cardiac Arrest. N Engl J Med. 2026 Jun 10 Background and introduction  Hypoxic-ischemic encephalopathy (HIE) may ensue in patients resuscitated from cardiac arrest, with devastating consequences. One of the mechanisms of i...

Lim WS, Bion J, Dark P, Finn A, et al. Procalcitonin testing combined with NEWS2 evaluation compared with usual care based on NEWS2 in adults presenting to emergency departments with suspected sepsis (PRONTO): a pragmatic, open-label, multicentre, randomised controlled trial. Lancet Respir Med. 2026;14:683–696 Introduction Early recognition and prompt treatment of sepsis are piv...