Biomedical Research and Therapy

Background: Conventional pharmacological and interventional treatments for chronic pain secondary to intervertebral disc herniation (IVDH) often provide only temporary symptomatic relief and carry significant adverse effect...

Background: Although overdose-induced acute hepatic failure following acetaminophen (APAP) administration is well documented, clinical studies have also reported myocardial infarction, cardiac dysfunction, arrhythmias, pericarditis, and cardia...

Hantavirus infection is an underrecognized infectious etiology of acute kidney injury (AKI), with hemorrhagic fever with renal syndrome (HFRS) defining its dominant renal phenotype. Kidney involvement spans from transient urinary abnormalities to s...

Introduction: Acral melanoma (AM) is the most prevalent melanoma subtype in Asian populations; however, long-term survival data from Southeast Asia, particularly Vietnam, remain scarce. This study aimed to investigate the clinicopathological characteristics and prognostic factors influencing overall survival (OS) in a Vietnamese cohort of patients with AM.

Background: Brominated flame retardants (BFRs) are persistent and ubiquitous environmental contaminants with recognized endocrine-disrupting potential, raising concern regarding their possible contribution to human carcinogenesis. This systematic review, conducted in accordance with the PRISMA guidelines, evaluated the association between BFR exposure and hum...