2minutemedicine

1. In an observational study of pediatric patients, melatonin use may be associated with a decreased percentage of rapid eye movement (REM) sleep compared to melatonin nonusers. Evidence Rating Level: 2 (Good) Melatonin has been used by up to 19% of pediatric patients in the past 30 days. It is available without a prescription, and […]

1. In patients with estrogen receptor (ER)+ and human epidermal growth factor receptor 2 (HER2)- breast cancer, certain tumour microenvironments (TMEs) were associated with improved breast cancer progression and treatment response to tamoxifen (Nolvadex). Evidence Rating Level: 1 (Excellent) The TME of tumour, immune, and stromal cells varies depending on breast cancer estrog...

1. A health coaching intervention combined with self-measured blood pressure (SMBP) monitoring for postpartum women was associated with significantly greater engagement with primary care and significantly greater reductions in systolic and diastolic blood pressure (BP). Evidence Rating Level: 1 (Excellent) Hypertensive disorders of pregnancy (HDP) affect up to 16% of pregnanc...

1. In adult women with endometriosis, surgery was associated with an increased quality of life independent of their #Enzian classification. Evidence Rating Level: 2 (Good) Endometriosis affects 7-10% of women of reproductive age and has a heterogeneous presentation, ranging from superficial peritoneal implants to involvement of retroperitoneal structures. The wide range of sy...

1. In critically injured trauma patients with difficult airways, there were no statistically significant differences in first-pass success between bougie-guided and stylet-guided intubation.  Evidence Rating Level: 1 (Excellent) First-pass intubation failure during emergency airway management is associated with hypoxia, aspiration, hemodynamic instability, and cardiac arrest....